The fresh or dried fruits of different Capsicum species are used medicinally. Capsicum oleoresin is prepared by extracting the crushed capsicum with volatile solvents by percolation method. Preparation made from the oleoresin in cayenne and oleoresin’s isolated constituent ‘Capsaicin’ is used as topical analgesic in OTC (over the counter) market. The herb is indigenous to Mexico and Central America. Methyl salicylate, menthol and camphor are originally derived from plants. Methyl salicylate is derived from oil of wintergreen, menthol is derived from mint and camphor is derived from a number of plants including Peppermint, Eucalyptus and Cedar.