Covid-19 Info:
We keep delivering!
We have COVID-19 Safety Plan and are committed to keeping you safe.
Dosage Form | |
---|---|
Strength | 0.25 mcg |
Generic Names | |
Manufacturer |
The first step involved in the activation of vitamin D3 is a 25-hydroxylation which is catalysed by the 25-hydroxylase in the liver and then by other enzymes. The mitochondrial sterol 27-hydroxylase catalyses the first reaction in the oxidation of the side chain of sterol intermediates. The active form of vitamin D3 (calcitriol) binds to intracellular receptors that then function as transcription factors to modulate gene expression. Like the receptors for other steroid hormones and thyroid hormones, the vitamin D receptor has hormone-binding and DNA-binding domains. The vitamin D receptor forms a complex with another intracellular receptor, the retinoid-X receptor, and that heterodimer is what binds to DNA. In most cases studied, the effect is to activate transcription, but situations are also known in which vitamin D suppresses transcription. Calcitriol increases the serum calcium concentrations by: increasing GI absorption of phosphorus and calcium, increasing osteoclastic resorption, and increasing distal renal tubular reabsorption of calcium. Calcitriol appears to promote intestinal absorption of calcium through binding to the vitamin D receptor in the mucosal cytoplasm of the intestine. Subsequently, calcium is absorbed through formation of a calcium-binding protein.
৳ 15.00
In stock
Dosage Form | |
---|---|
Strength | 0.25 mcg |
Generic Names | |
Manufacturer |
Search from thousands of medicine and health products for your daily needs. Preskriptionpoint will ship them to your door with our fastest facility.
Accounts
Stop! This is a test environment, not a live site yet. please wait until the final publication for any order.
Something isn’t Clear?
Feel free to contact us, and we will be more than happy to answer all of your questions.
Covid-19:
We keep delivering!