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| Dosage Form | |
|---|---|
| Strength | 20 mg/ml |
| Pack Size | 100 mg vial, 40 mg vial |
| Generic Names | |
| Manufacturer |
Irinotecan inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex. The formation of this ternary complex interferes with the moving replication fork, which induces replication arrest and lethal double-stranded breaks in DNA. As a result, DNA damage is not efficiently repaired and apoptosis (programmed cell death) occurs.
| Dosage Form | |
|---|---|
| Strength | 20 mg/ml |
| Pack Size | 100 mg vial, 40 mg vial |
| Generic Names | |
| Manufacturer |
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Covid-19:
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