Clindamycin is a lincosamide antibiotic. Clindamycin inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome. It has activity against aerobic gram-positive cocci, including. Staphylococcus aureus, Staphylococcus epidermidis (penicillinase and non-penicillinase producing strains), Streptococci, Pneumococci. Anerobic gram-negative bacilli including; Bacteroids species, Fusobacterium species. Anaerobic gram-positove non-spore forming bacilli including. Propionibacterium species, Eubacterium species, Actinomyces species, Peptostreptococcus species, Microaerophillic streptococci, C. perferinges.