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Additional Product Details
Dosage Form

Strength

20 mg/ml

Pack Size

100 mg vial.

Generic Names

Manufacturer

Prescribing info

Campto

Irinotecan inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex. The formation of this ternary complex interferes with the moving replication fork, which induces replication arrest and lethal double-stranded breaks in DNA. As a result, DNA damage is not efficiently repaired and apoptosis (programmed cell death) occurs.

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Additional Product Details
Dosage Form

Strength

20 mg/ml

Pack Size

100 mg vial.

Generic Names

Manufacturer

Prescribing info

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